Renewal
We conducted a randomized placebo-controlled clinical trial with adults aged 40-65 years old. After 4 months, participants who received a daily 500 mg dose of Mitopure (Urolithin A) had an increase in mitophagy of +39% over placebo.
Strength
We conducted a randomized placebo-controlled clinical trial with adults aged 40-65 years old. After 4 months, participants who received a daily 500 mg dose of Mitopure (Urolithin A) had a significant improvement in muscle strength, compared with participants in the placebo group.
Bioavailability
Urolithin A is a molecule produced by gut microflora from foods rich in ellagitannins, such as pomegranates. Not everyone has a microbiome capable of producing Urolithin A, making supplementation an appealing strategy. We conducted a human clinical trial to measure the ability of Mitopure (Urolithin A) to overcome both microbiome and dietary variability. We found that a 500mg dose of Mitopure delivers a 6-fold exposure to Urolithin A than 100% pomegranate juice.